I have used R4 for 2 weeks now. It has helped my tmj, and trigeminal neuralgia, as well as a constant pain in my neck and back that is normally about a 6.5 on the 1-10 scale. The pain is now at about a 2, and I have not had to take my protonics, or carbatrol today. The carbatrol is like taking chemo! I have no nausea today! R4 doesn't get you high, but it is the best bud I can smoke. MMJ R4 is a real medicine for what I need. I will use other MMJ strains for other problems.